2025年3月29日至31日，第74届美国心脏病学会年度科学会议（ACC.25）将在美国芝加哥盛大举行。作为全球心血管领域最具影响力的学术会议之一，ACC.25将汇聚来自世界各地的顶尖专家、学者，共同探讨心血管疾病预防、诊断和治疗的最新突破与前沿进展。在为期3天的会议中，共设置了6场Late-Breaking Clinical Trials（LBCT），23项重磅研究结果即将揭晓，涵盖从新型药物治疗到创新介入技术的多个领域，有望为心血管医学实践带来革命性变革。
严道医声网特此汇总整理，供业内人士速览并提前规划参会重点！
会议日程：3月29日（芝加哥）
Late-Breaking Clinical Trials I (Session 102)/Joint American College of Cardiology/Journal of the American College of Cardiology
北京时间：3月29日 22:30-23:30
Primary and Secondary Outcomes of the Women's Ischemia Trial to Reduce Events in Non-Obstructive Coronary Artery Disease
减少女性非阻塞性冠状动脉疾病缺血事件试验的主要和次要研究结果
讲者：Eileen Handberg
The Effect of Once-weekly Subcutaneous Semaglutide on Functional Capacity in People With Type 2 Diabetes and Peripheral Artery Disease: Primary Results From the Phase 3b, Randomized, Placebo-Controlled, Double Blind Stride Trial
每周一次皮下注射司美格鲁肽对2型糖尿病合并外周动脉疾病患者功能的影响：一项来自 3b期、随机、安慰剂对照、双盲“Stride”试验的初步结果
讲者：Marc Bonaca
Extended Anticoagulant Treatment With a Reduced Versus Full Dose Apixaban in Patients With Cancer-Associated Venous Thromboembolism: The API-CAT Study
癌症相关静脉血栓栓塞症患者采用减量和全剂量阿哌沙班进行延长抗凝治疗：API-CAT 研究
讲者：Isabelle MAHE
Late-Breaking Clinical Trials II (Session 103)
北京时间：3月30日 00:30-01:30
Efficacy of Rivaroxaban Versus Warfarin in Patients With Acute Left Ventricular Thrombus Following Myocardial Infarction: An Open-Label Randomized Controlled Trial RIVAWAR Trial Investigators
利伐沙班与华法林在急性心肌梗死后左心室血栓患者中的疗效比较：一项开放标签随机对照试验——RIVAWAR试验
讲者：Jehangir Ali Shah
Four-Factor Prothrombin Complex Concentrate is Superior to Frozen Plasma in Bleeding Adult Cardiac Surgery Patients With Coagulopathy — Results From a Phase 3, Randomized, Active-Control Study
Ⅳ因子凝血酶原复合物浓缩液在凝血功能障碍的出血成年心脏手术患者中的疗效优于冰冻血浆——一项 3期、随机、活性对照研究
讲者：Keyvan Karkouti
The Main Results of the Phase 3 Reverse-it Trial
REVERSE-IT 3期试验的主要结果
讲者：Deepak Bhatt
Stratified Randomization Study to Compare Different Duration of Dual Antiplatelet Therapy After Coronary Stenting in Either High or Low Bleeding Risk Population
分层随机对照研究：比较冠状动脉支架置入术后不同时长的双重抗血小板治疗在高出血风险人群和低出血风险人群中的效果差异
讲者：Hyo-Soo Kim
Late-Breaking Clinical Trials III (Session 104)/Joint American College of Cardiology/Journal of the American Medical Association
北京时间：3月30日 02:30-03:30
Oral Semaglutide Reduces Cardiovascular Events in People With Type 2 Diabetes With Atherosclerotic Cardiovascular and/or Chronic Kidney Disease: Primary Results From the SOUL Randomized Trial
口服司美格鲁肽可降低合并动脉粥样硬化性心血管疾病和/或慢性肾病的2型糖尿病患者心血管事件：SOUL 随机试验的初步结果
讲者：Darren McGuire
Efficacy of Lorundrostat, A Novel Aldosterone Synthase Inhibitor, In Patients With Uncontrolled Hypertension on a Standardized Antihypertensive Medication Regimen
新型醛固酮合酶抑制剂Lorundrostat对标准降压药物治疗方案下血压控制不佳患者中的疗效
讲者：Luke Laffin
Development and External Validation of a Deep Learning Electrocardiogram Model For Risk Stratification of Coronary Revascularization Need in the Emergency Department
急诊科用于冠状动脉旁路移植术需求风险分层的深度学习心电图模型的开发及外部验证
讲者：Antonius Buescher
Dapagliflozin in Patients Undergoing Transcatheter Aortic Valve Implantation
达格列净在经导管主动脉瓣植入术患者中的应用
讲者：Sergio Raposeiras Roubin
会议日程：3月30日（芝加哥）
Featured Clinical Research IV (Session 112)
北京时间：3月30日 21:00-22:00
Comparative Effectiveness of Mobile Integrated Health Versus a Transitions of Care Coordinator in Patients With Heart Failure: Results From the MIGHTy-Heart Trial、
移动综合健康服务与护理过渡协调员在心力衰竭患者中的疗效比较：MIGHTy-Heart 试验的结果
讲者：Ruth Masterson Creber
Liberal Fluid Intake Versus Fluid Restriction in Chronic Heart Failure
慢性心力衰竭患者中自由液体摄入与限制液体摄入的比较
讲者：Roland Van Kimmenade
The Equiox Study: Evaluating Pulse Oximeter Bias Across a Range of Skin Pigment in Critically Ill Adults
EQUIOX研究：评估不同肤色危重症成人的脉搏血氧仪偏差
讲者：Carolyn Hendrickson
Ferric Carboxymaltose Assessment of Morbidity and Mortality in Patients With Iron Deficiency and Chronic Heart Failure (FAIR-HF2) Trial
羧基麦芽糖铁对缺铁性贫血合并慢性心力衰竭患者死亡率和发病率的影响（FAIR-HF2）
讲者：Stefan Anker
Late-Breaking Clinical Trials V (Session 107)/Joint American College of Cardiology/New England Journal of Medicine
北京时间：3月30日 23:00-24:00
Routine Cerebral Embolic Protection in Transcatheter Aortic Valve Implantation: The British Heart Foundation (BHF) PROTECT-TAVI Trial
经导管主动脉瓣植入术中的常规脑栓塞防护：英国心脏基金会（BHF）PROTECT-TAVI 试验
讲者：Rajesh Kharbanda
Clinical And Echocardiographic Outcomes Among the First 500 Patients Treated With a Dedicated Transcatheter Aortic Valve For Pure Aortic Regurgitation in the Align-AR Clinical Trial
Align-AR 临床试验中500名接受专用经导管主动脉瓣治疗的单纯主动脉瓣反流患者中的临床和超声心动图结果
讲者：Raj Makkar
5-year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis
低风险主动脉瓣狭窄患者经导管或外科主动脉瓣置换术后 5 年的结果
讲者：Michael Reardon
Comparison of Angiography-Derived Fractional Flow Reserve-Guided and Intravascular Ultrasound-Guided Percutaneous Coronary Intervention Strategies: The FLAVOUR II Trial
血管造影衍生的血流储备分数（FFR）指导与经血管超声指导的经皮冠状动脉介入治疗的比较：FLAVOUR II 试验
讲者：浙江大学医学院附属第二医院 王建安教授
Late-Breaking Clinical Trials VI (Session 108)
北京时间：3月31日 00:30-01:30
Two-Year Outcomes of Transcatheter Tricuspid Valve Edge-to-Edge Repair For Tricuspid Regurgitation: The Triluminate Pivotal Trial
经导管三尖瓣边缘对缘修复术治疗三尖瓣反流的2年结局：TriLuminate 试验
讲者：Saibal Kar
Fractional Flow Reserve Guided Percutaneous Coronary Intervention Compared With Bypass Surgery: Final 5 Year Results of the Fractional Flow Reserve Versus Angiography For Multivessel Evaluation 3 Trial
血流储备分数指导的经皮冠状动脉介入治疗与冠状动脉旁路移植术的比较：多支病变FFR vs. 造影评估（FAME）3试验的最终5年结果
讲者：William Fearon
Clopidogrel Versus Aspirin For Long-Term Maintenance Monotherapy in Patients With High Ischemic Risk After Percutaneous Coronary Intervention
氯吡格雷与阿司匹林在经皮冠状动脉介入治疗后高缺血风险患者长期维持单药治疗的比较
讲者：Joo-Yong Hahn
Alliance For Secondary Prevention After an Acute Coronary Syndrome
急性冠状动脉综合征后二级预防联盟
讲者：Giulia Magnani
