心脏代谢合并症作为心血管领域的多发病，其管理策略一直是医学研究的热 点和难点。这类疾病涉及多个系统的病理生理变化，治疗难度极大。然而，正是这些挑战，促使我们不断探索和创新。
Heart metabolic syndrome, as a prevalent disease in the field of cardiovascular medicine, has always been a hot and difficult topic in medical research. These diseases involve pathophysiological changes in multiple systems, posing significant challenges in treatment. However, it is these challenges that drive us to constantly explore and innovate.
At the upcoming 18th Oriental Congress of Cardiology (OCC 2024) and the World Congress of Cardiology (WCC 2024), experts will delve deeply into the pathogenesis, diagnostic techniques, treatment strategies, and future development directions of heart metabolic syndrome. We look forward to this grand event, hoping that it will promote research progress in the management of heart metabolic syndrome and bring more hope to patients.
论坛名称：WCC-多发病率与代谢论坛
论坛时间：2024年6月27日 星期四
论坛地点：上海国际会议中心黄河厅
论坛坛主：伦敦卫生与热带医学学院Pablo Perel教授；华中科技大学同济医学院附属协和医院黄恺教授
Forum Name: WCC-Multi-morbidity and metabolism Forum
Forum Date: Thursday,June 27 2024
Forum Venue: Yellow River Hall，Shanghai International Conference Centre
Forum Chairs:
Professor Pablo Perel, University of London, London School of Hygiene & Tropical Medicine;
Professor Huang Kai, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Pablo Perel教授
黄恺教授
肥胖与胰岛素抵抗
Obesity and Insulin Resistance
在当今社会，随着生活方式的改变和营养过剩的问题日益突出，肥胖已成为一个全球性的公共卫生问题。而肥胖背后隐藏的一个关键病理机制，正是胰岛素抵抗。
作为这一领域的权威专家，上海市糖尿病研究所的贾伟平院士将为我们深入解析胰岛素抵抗与肥胖之间的紧密关系，以及这一关系如何影响并加剧心脏代谢合并症这一多发病的发生与发展。
In today's society, with the changing lifestyles and the increasingly prominent issue of nutritional excess, obesity has become a global public health concern. A key pathological mechanism underlying obesity is insulin resistance.
Academician Jia Weiping, an authoritative expert in this field from the Shanghai Diabetes Institute, will delve into the close relationship between insulin resistance and obesity, as well as how this relationship affects and exacerbates the occurrence and development of the prevalent heart metabolic syndrome.
Diabetes Increases the Risk of Cardiovascular Diseases
在中国，心血管疾病的发病率与致死率持续高居不下，成为威胁国民健康的头号杀手。据《中国心血管健康与疾病报告2022》显示，心血管疾病现患人数已超3.3亿，每十秒钟就有一人因心血管疾病离世。
其中，糖尿病作为心血管疾病的重要风险因素，其负担不容忽视。糖尿病患者罹患心血管疾病，尤其是动脉粥样硬化性心血管疾病（ASCVD）的风险大幅上升。华中科技大学同济医学院附属协和医院的黄恺教授将详细阐述这一沉重的糖尿病负担，以期探寻出新的保护心血管健康的有效路径。
In China, the incidence and mortality rates of cardiovascular diseases continue to rank at the top, posing a significant threat to national health. According to the "China Cardiovascular Health and Diseases Report 2022," the number of people currently suffering from cardiovascular diseases has exceeded 330 million, and every ten seconds, someone dies from cardiovascular diseases.
Among these, diabetes serves as a significant risk factor for cardiovascular diseases, and its burden cannot be overlooked. The risk of developing cardiovascular diseases, especially atherosclerotic cardiovascular diseases (ASCVD), is significantly increased for diabetic patients. Professor Huang Kai from the Union Hospital affiliated with Tongji Medical College of Huazhong University of Science and Technology will elaborate on this heavy burden of diabetes, aiming to explore new effective paths for protecting cardiovascular health.
管理新方法，重获健康！
New Management Approaches for Regaining Health!
在应对复杂且多发的心脏代谢合并症挑战时，科研界正积极探索新的管理策略。哈佛大学医学院的Evan Rosen教授将揭示一种创新的方法：通过催产素能交感神经元群来控制脂肪分解，这不仅深化了我们对脂肪代谢调控机制的理解，更为心脏代谢合并症的管理提供了强有力的新工具。
同时，美国德州大学西南医学中心的Jay D Horton教授将引领我们探索PCSK9从基因研究到实际治疗的转化之旅。PCSK9作为调控胆固醇代谢的核心因子，其基因变异对心脏代谢健康有着深远影响。Horton教授的报告将揭示如何从基因层面出发，精准地治疗心脏代谢合并症。
In addressing the complex and prevalent challenges of heart metabolic syndrome, the scientific community is actively exploring new management strategies. Professor Evan Rosen from the United States will reveal an innovative method: controlling fat decomposition through oxytocin-sensitive sympathetic neurons, which not only deepens our understanding of the regulatory mechanism of fat metabolism but also provides a powerful new tool for managing heart metabolic syndrome.
Meanwhile, Professor Jay D Horton from UT Southwestern Medical Center will guide us through the journey of PCSK9 from genetic research to practical treatment. As a core factor regulating cholesterol metabolism, genetic variations in PCSK9 have profound impacts on heart metabolic health. Professor Horton's report will reveal how to precisely treat heart metabolic syndrome from the genetic perspective.
在WCC-多发病率与代谢论坛即将揭幕之际，我们对这场汇聚全球智慧与力量的盛会充满了无限的期待。这不仅仅是一场学术交流的盛会，更是心血管健康事业砥砺前行的重要里程碑。我们坚信，通过此次论坛的深入研讨与交流，我们将迎来对心脏代谢合并症这一多发病的全新认识和策略。这些新的见解和方法，将为我们提供更精准、更有效的治疗方案，为患者带来希望与生机！
As the WCC-Multimorbidity and Metabolism Forum is set to kick off, we are filled with immense anticipation for this event that brings together global wisdom and strength. This is not just an academic exchange event, but also an important milestone for the advancement of cardiovascular health. We firmly believe that through in-depth discussions and exchanges at this forum, we will gain new insights and strategies for the prevalent heart metabolic syndrome. These new perspectives and methods will provide us with more precise and effective treatment options, bringing hope and vitality to patients!
