心血管与瓣膜发育和疾病:青年论坛
Cardiovascular Development and Heart Valve Disease: Youth Forum
04/18 16:00-17:40
纽约厅(二楼) (Room New York(2F))
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16:00-17:40
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16:00-17:40
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16:00-16:10脯氨酸羟化酶P4HA1介导核孤儿受体NR4A1琥珀酰化促进主动脉瓣钙化的机制研究P4HA1-Mediated Succinylation of Orphan Nuclear Receptor NR4A1 Promotes Aortic Valve Calcification
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16:10-16:20PEN2通过稳定SLC25A51介导线粒体与细胞核间NAD⁺再分布抑制动脉钙化PEN2 Stabilizes SLC25A51 to Inhibit Arterial Calcification Through NAD+ redistribution Between Mitochondrion and Nucleus
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16:20-16:30黄芪甲苷IV通过抑制CCL2/NF-κB信号通路改善LPS诱导的大鼠心肌重塑及功能障碍Astragaloside IV Ameliorates LPS-Induced Myocardial Remodeling and Dysfunction in Rats by Inhibiting the CCL2/NF-κB Signaling Pathway
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16:30-16:40三尖瓣关闭不全患者循环血miRNA表达差异Differential Expression of Circulating miRNAs in Patients with Tricuspid Regurgitation
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16:40-16:50UBC9介导的SUMO化修饰通过调控VSMCs中Ryr2依赖性钙稳态减轻血管钙化UBC9-mediated SUMOylation Attenuates Vascular Calcification by Regulating Ryr2-Dependent Calcium Homeostasis in VSMCs
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16:50-17:00E3泛素连接酶在钙化性主动脉瓣疾病发生发展的作用The Role of E3 Ubiquitin Ligases in the Pathogenesis and Progression of Calcific Aortic Valve Disease
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17:00-17:10CD34+ 瓣膜间质祖细胞通过PDGFR-JNK-JunB信号轴促进老年退行性主动脉瓣膜硬化CD34+ progenitor VICs Promote Aging-associated Aortic Valve Sclerosis Through PDGFR-JNK-JunB axis
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17:10-17:20暴发性心肌炎早期损伤机制与干预策略探索Early Injury Mechanisms and Intervention Strategies in Fulminant Myocarditis
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17:20-17:40讨论Discussion